LH and you will FSH, luteinizing and hair follicle-revitalizing hormonal, respectively; SHBG, intercourse hormones-joining globulin; IGF-I, insulin-instance progress factor We

LH and you will FSH, luteinizing and hair follicle-revitalizing hormonal, respectively; SHBG, intercourse hormones-joining globulin; IGF-I, insulin-instance progress factor We

Adverse feel, bloodstream matters and chemistries, PSA, plasma lipids, complete and you can free testosterone, luteinizing hormone (LH), intercourse steroid-joining globulin (SHBG), and you will insulin-instance development foundation We (IGF-I) profile was in fact mentioned sporadically throughout manage and you can medication symptoms. Serum full testosterone is measured because of the an enthusiastic immunoassay (8-11); totally free testosterone from the harmony dialysis (43); LH, SHBG, and PSA from the immunoradiometric assays (9-11); and you will IGF-We because of the acid-ethanol extraction and you can immunoassay (28). New sensitivities and you can intra- and interassay coefficients away from version to possess hormonal assays have been below: complete testosterone (0.6 ng/dl), 8.dos and thirteen.2%; 100 % free testosterone (0.twenty two pg/ml), cuatro.dos and you can several.3%; LH (0.05 You/l), 10.7 and you will thirteen.0%; SHBG (six.25 nmol/l), 4 and you will six%; PSA (0.01 ng/ml), 5.0 and you may 6.4%; and you may IGF-We (80 ng/ml), cuatro and you can six%, respectively. These assays were validated in earlier times (8-11).

Mathematical analyses.

All variables were examined for their distribution characteristics. Variables not meeting the assumption of a normal distribution were log-transformed and retested. An ANOVA was used to compare change from baseline in outcome measures among the five groups. All outcome measures were analyzed using a paired t-test to detect a nonzero change from baseline within each group.Continue Reading